Thursday, December 15, 2011

Hemophilia


Hemophilia is a Sex-Linked bleeding disorder that slows blood clotting. It can cause people to bleed more often from little injuries and bleed alot longer from things such as surgery, any injury, or having a tooth pulled. Hemophilia can cause severe internal bleeding into joints, muscles, organs, or the brain. It can cause massive swelling and even death.
Hemophilia A is caused my a change in the F8 gene and Hemophilia B is caused by a mutation in the F9 gene. A is the classic one while B is known as christmas disease. A form of B is known as hemophilia B Leyden and that causes excessive bleeding in adulthood but gets better after puberty. Hemophila C is the rarest and takes much longer to clot.
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The symptoms are simply bleeding. They may not be noticed until later in life during surgery or after trauma. Diagnostics and Detection are normally after a severe bleeding episode.
People can be treated by receiving the clotting factor by intravenous infusions which is through a vein.
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Hemophilia is more common in men. 1 in 400 to 1 in 5000 males are born with Hemophilia A and 1 in 20,000 are born with Hemophilia B worldwide. it affects all ethnic groups.
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Life expectancy isnt really affected but some may bleed to death and internal bleeding may cause problems.

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